{"text_format":"1","workbook":"xlsx","n_sheets":5,"sheets":["INSTRUCTIONS","Establishment details","Procedure details","mismac","Lists"],"not_rendered":{"charts":0,"images":3,"macros":1,"external_links":0,"defined_names":49,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900"}

{"sheet":"INSTRUCTIONS","index":0,"n_rows":40,"n_cols":1,"rows_kept":40,"cut":false,"hidden":false,"merged":[[0,0,0,3],[39,0,39,1]]}
["Animal use data 2016\n\nPLEASE ENSURE MACROS ARE ENABLED TO ENSURE THIS SPREADSHEET FUNCTIONS PROPERLY \n\n- If the security warning appears, please follow the instructions below (see step 1 for Windows users or step M for Mac users)\n- If no security warning appears, please continue to the next page\n\nYou will be asked to resubmit the form if macros have not been enabled\n\nThe deadline for providing this return is 31 January 2017\n\nIf you require assistance, contact ASRU Business Support Team at ROPReturns@homeoffice.gsi.gov.uk or phone 020 7035 8625"]
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["    For Windows users (for Mac users, see below). Please note, this is an example and the macro message may not look exactly like this."]
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["If you require assistance, contact ASRU Business Support Team at ROPReturns@homeoffice.gsi.gov.uk or phone 020 7035 0583 / 8625 "]
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["    For Mac users (for Windows users, see above). Please note, this is an example and the macro message may not look exactly like this."]
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["M) "]

{"sheet":"Establishment details","index":1,"n_rows":63,"n_cols":3,"rows_kept":63,"cut":false,"hidden":false,"merged":[[0,0,0,3],[1,0,1,3],[2,0,2,3],[27,1,27,2],[26,1,26,2]]}
[{"$f":"CONCATENATE(\"Animal use data \",C24)","v":"Animal use data 2016"}]
["PLEASE ENSURE MACROS ARE ENABLED TO ENSURE THIS SPREADSHEET FUNCTIONS PROPERLY (SEE INSTRUCTIONS)\nIf you require assistance, contact ASRU Business Support Team at ROPReturns@homeoffice.gsi.gov.uk or phone 020 7035 8625 "]
["Once macros are enabled, the \"procedure details\" tab will only appear if:\n'Were any procedures carried out and completed in the reported year?' is Yes and \n'Were only 'protected' embryonic forms used in the reported year?' is No\n\nThroughout this workbook, where a cell has a drop-down box (to the right of it), please use it to enter data"]
[null,"Country:","United Kingdom"]
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[null,"Name (if you are NOT the project licence holder, please provide their name in the Additional comments box below):"]
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[null,"Establishment address (including postcode):"]
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[null,"Email address:"]
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[null,"Telephone number:"]
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[null,"Serial number (for Home Office use only):"]
[null,null,{"$f":"RIGHT(C17,4)","v":""}]
[null,"Establishment licence number (see comment in entry box to the right)"]
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[null,"Project licence number (see comment in entry box to the right)"]
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[null,"Reported year:",2016]
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[null,"Were any procedures carried out and completed in the reported year?"]
[null,"If \"No\", do not populate the rest of this workbook.\nThe \"procedure details\" tab will only appear if this is \"Yes\" and the below row (embryonic forms) is \"No\"."]
[null,"Click here for the guidance on how to complete this form."]
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[null,"Were only 'protected' embryonic forms (i.e. of sufficient age to be regulated) used in the reported year? (See comment in entry box to the right)"]
[null,"          If \"Yes\", the procedure details tab will not appear as it should not be completed."]
[null,"Were any endangered species listed in Annex A to Council Regulation EC 338/97 used in any procedures in the reported year? "]
[null,"          If \"Yes\", please provide details in the Additional comments box below."]
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[null,"Were neuromuscular blocking agents (NMBA) used in any procedures"]
[null,"in the reported year?"]
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[null,"If yes to the above, was general anaesthesia used throughout the"]
[null,"entire period of neuromuscular blockade?"]
[null,"          If \"No\", please provide details in the Additional comments box below."]
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[null,"Were any rodenticide trials undertaken in the reported year?"]
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[null,"Additional comments:"]
[null,"          e.g. name of project licence holder (if not provided above); details"]
[null,"          regarding Annex A listed species; details regarding use of NMBA"]
[null,"          without general anaesthesia."]
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[null,{"$f":"IF(mismac!Y305=0,\"ND_\",\"D_\")","v":"ND_"}]
[null,{"$f":"IF(AND(C26=\"Yes\",C30=\"No\"),1,0)","v":0}]
[null,{"$f":"COUNTA(C19,C22,C26)","v":0}]
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[null,null,{"$f":"IF(AND(C8=\"\",C9=\"\",C10=\"\",C11=\"\"),1,0)","v":1}]
[null,null,{"$f":"IF(AND(C44=\"\",C45=\"\",C46=\"\",C47=\"\", C48=\"\",C49=\"\",C50=\"\",C51=\"\",C52=\"\",C53=\"\"),1,0)","v":1}]

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["EU Submission *","Id 1","Id 2","Id 3","Animal Species","Specify other","No of Procedures","Re-use","Place of birth","Non-human Primate (NHP) Place of birth","Non-human Primate (NHP) Generation","Genetic status","Creation of new Genetic Line","Purpose","Sub-purpose, if applicable","Specify other","Testing by legislation","Specify other","Legislative Requirements (origin of the legislation) ","Actual Severity","Custom Severity","Techniques of Special Interest","Comments 1: for the attention of the Home Office","Comments 2: for personal use e.g. study numbers"]

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[1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,"counta",1,"other species","primates","threshold 999","threshold 9999","PR","REUSE","other purpose","other testing by legislation - LT10","PRIMATES > 99","NON PRIMATES GREATER THAN 999","NON PRIMATES GREATER THAN 9999","sub purpose","Schedule 2 and non-registered breeder","Sub-threshold and non-breeding","Severe, >999 and breeding","Non genetically altered and purpose breeding","GAA Pigs/Sheep Schedule 2 and non reg breeder"]
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["[PB3] ","[PB3] (Basic Research) Nervous System",null,null,null,null,null,null,null,"A3","Guinea-Pigs (Cavia porcellus)",null,"[A3] Guinea-Pigs (Cavia porcellus)",null,null,null,1,1,null,"Bulgaria",null,null,"[LO3] Legislation satisfying Non-EU requirements only",null,null,null,null,null,null,"[LT3] Medical devices legislation",null,null,null,null,null,null,null,"[SV2] Mild",null,null,null,null,null,"[O2_1] Animals born in the UK but NOT at a licensed establishment",1,null,null,null,null,"[NHPO2] Animals born in rest of Europe","[NHPO1_1B] Animals born in the UK but NOT at a licensed establishment",null,null,null,null,null,null,"[NHPG3] F2 or greater",null,null,null,"[GS3] Genetically altered with a harmful phenotype",null,null,null,null,null,null,2015,null,null,"[PE40] Protection of the natural environment in the interests of the health or welfare of human beings or animals",null,null,null,null,null,null,null," "]
["[PB4] ","[PB4] (Basic Research) Respiratory System",null,null,null,null,null,null,null,"A4","Hamsters (Syrian) (Mesocricetus auratus)",null,"[A4] Hamsters (Syrian) (Mesocricetus auratus)",null,null,null,1,1,null,"Croatia",null,null,null,null,null,null,null,null,null,"[LT4] Industrial chemicals legislation",null,null,null,null,null,null,null,"[SV3] Moderate",null,null,null,null,null,"[O2_2] Animals born in the EU (non UK) but NOT at a registered breeder",1,null,null,null,null,"[NHPO3] Animals born in Asia","[NHPO1_2B] Animals born in the EU (non UK) but NOT at a registered breeder",null,null,null,null,null,null,"[NHPG4] Self-sustaining colony",null,null,null,null,null,null,null,null,null,null,2016,null,null,"[PS41] Preservation of species",null,null,null,null,null,null,null," "]
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["[PB11]","[PB11] (Basic Research) Multisystemic",null,null,null,null,null,null,null,"A11","Ferrets (Mustela putorius furo)",null,"[A11] Ferrets (Mustela putorius furo)",null,null,1,null,1,null,"Greece",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Sub-threshold",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PB4] Respiratory System",null,null,null,null,"Routine production"]
["[PB12]","[PB12] (Basic Research) Ethology / Animal Behaviour /Animal Biology",null,null,null,null,null,null,null,"A12","Other carnivores (other Carnivora)",null,"[A12] Other carnivores (other Carnivora)",1,null,1,null,null,null,"Hungary",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Threshold",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PB5] Gastrointestinal System including Liver",null,null,null,null,null,null,null,null,"[PB13] Other",null,"PB13"]
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["[PT21]","[PT21] (Trans/Appl Research) Human Cancer",null,null,null,null,null,null,null,"A14","Pigs (Sus scrofa domesticus)",null,"[A14] Pigs (Sus scrofa domesticus)",null,null,1,null,null,1,"Italy",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"proc",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PB6_2] Dentistry",null,null,null,null,"[PR62] Pyrogenicity testing",null,null,null,"[PR64] Other quality controls",null,"PR64"]
["[PT22]","[PT22] (Trans/Appl Research) Human Infectious Disorders",null,null,null,null,null,null,null,"A15","Goats (Capra aegagrus hircus)",null,"[A15] Goats (Capra aegagrus hircus)",null,null,1,null,null,null,"Latvia",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Yes",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PB7] Immune System",null,null,null,null,"[PR63] Batch potency testing",null,null,null,"[PR71] Other efficacy and tolerance testing",null,"PR71"]
["[PT23]","[PT23] (Trans/Appl Research) Human Cardiovascular Disorders",null,null,null,null,null,null,null,"A16","Sheep (Ovis aries)",null,"[A16] Sheep (Ovis aries)",null,null,1,null,null,1,"Lithuania",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"No",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PB8] Urogenital/Reproductive System",null,null,null,null,"[PR64] Other quality controls",null,null,null,"[PR82] Other lethal methods",null,"PR82"]
["[PT24]","[PT24] (Trans/Appl Research) Human Nervous and Mental Disorders",null,null,null,null,null,null,null,"A17","Cattle (Bos primigenius)",null,"[A17] Cattle (Bos primigenius)",null,null,1,null,null,null,"Luxembourg",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PB9] Sensory Organs (skin, eyes and ears)",null,null,null,null,null,null,null,null,"[PR103] Other",null,"PR103"]
["[PT25]","[PT25] (Trans/Appl Research) Human Respiratory Disorders",null,null,null,null,null,null,null,"A18","Prosimians (Prosimia)",null,"[A18] Prosimians (Prosimia)",null,1,null,null,1,null,"Malta",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"NMBA",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PB10] Endocrine System/Metabolism",null,null,null,null,"[PR51] Blood based products",null,null,null,"[PR106] Other",null,"PR106"]
["[PT26]","[PT26] (Trans/Appl Research) Human Gastrointestinal Disorders including Liver",null,null,null,null,null,null,null,"A19","Marmoset and tamarins (eg. Callithrix jacchus)",null,"[A19] Marmoset and tamarins (eg. Callithrix jacchus)",null,1,null,null,1,null,"Netherlands",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"No",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PB11] Multisystemic",null,null,null,null,"[PR52] Monoclonal antibodies",null,null,null,"[PT32] Other Human Disorders",null,"PT32"]
[{"$f":"MID(B22,1,8)","v":"[PT27_1]"},"[PT27_1] (Trans/Appl Research) Human Musculoskeletal Disorders",null,null,null,null,null,null,null,"A20","Cynomolgus monkey (Macaca fascicularis)",null,"[A20] Cynomolgus monkey (Macaca fascicularis)",null,1,null,null,1,null,"Poland",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Yes",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PB12] Ethology / Animal Behaviour /Animal Biology",null,null,null,null,"[PR53] Other"]
[{"$f":"MID(B23,1,8)","v":"[PT27_2]"},"[PT27_2] (Trans/Appl Research) Human Dentistry",null,null,null,null,null,null,null,"A21","Rhesus monkey (Macaca mulatta)",null,"[A21] Rhesus monkey (Macaca mulatta)",null,1,null,null,1,null,"Portugal",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PB13] Other"]
["[PT28]","[PT28] (Trans/Appl Research) Human Immune Disorders",null,null,null,null,null,null,null,"A22","Vervets Chlorocebus spp. (usually either pygerythrus or sabaeus)",null,"[A22] Vervets Chlorocebus spp. (usually either pygerythrus or sabaeus)",null,1,null,null,1,null,"Romania",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"TOSI",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Acute and sub-acute",null,null,null,"[PR81] LD50, LC50"]
["[PT29]","[PT29] (Trans/Appl Research) Human Urogenital/Reproductive Disorders",null,null,null,null,null,null,null,"A23","Baboons (Papio spp.)",null,"[A23] Baboons (Papio spp.)",null,1,null,null,1,null,"Slovakia",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"None",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PT21] Human Cancer",null,null,null,null,null,"[PR84] Skin irritation/corrosion",null,null,null,"[PR82] Other lethal methods"]
["[PT30]","[PT30] (Trans/Appl Research) Human Sensory Organ Disorders (skin, eyes and ears)",null,null,null,null,null,null,null,"A24","Squirrel monkey (eg. Saimiri sciureus)",null,"[A24] Squirrel monkey (eg. Saimiri sciureus)",null,1,null,null,1,null,"Slovenia",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Household product testing",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PT22] Human Infectious Disorders",null,null,null,null,null,"[PR85] Skin sensitisation",null,null,null,"[PR83] Non lethal methods"]
["[PT31]","[PT31] (Trans/Appl Research) Human Endocrine/Metabolism Disorders",null,null,null,null,null,null,null,"A25_1","Other species of Old World Monkeys (Cercopithecoidea)",null,"[A25_1] Other species of Old World Monkeys (Cercopithecoidea)",1,1,null,null,1,null,"Spain",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Use of ascites models for monoclonal antibody production",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PT23] Human Cardiovascular Disorders",null,null,null,null,null,"[PR86] Eye irritation/corrosion"]
["[PT32]","[PT32] (Trans/Appl Research) Other Human Disorders",null,1,null,null,null,null,null,"A25_2","Other species of New World Monkeys (Ceboidea)",null,"[A25_2] Other species of New World Monkeys (Ceboidea)",1,1,null,null,1,null,"Sweden",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Tobacco",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PT24] Human Nervous and Mental Disorders",null,null,null,null,null,"Repeated dose toxicity",null,null,null,"[PR87] up to 28 days"]
["[PT33]","[PT33] (Trans/Appl Research) Animal Diseases and Disorders",null,null,null,null,null,null,null,"A26","Apes (Hominoidea)",null,"[A26] Apes (Hominoidea)",null,1,null,null,1,null,"United Kingdom",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Alcohol",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PT25] Human Respiratory Disorders",null,null,null,null,null,"[PR90] Carcinogenicity",null,null,null,"[PR88] 29 - 90 days"]
["[PT34]","[PT34] (Trans/Appl Research) Animal Welfare",null,null,null,null,null,null,null,"A27","Other Mammals (other Mammalia)",null,"[A27] Other Mammals (other Mammalia)",1,null,1,null,null,null," ",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PT26] Human Gastrointestinal Disorders including Liver",null,null,null,null,null,"[PR91] Genotoxicity",null,null,null,"[PR89] > 90 days"]
["[PT35]","[PT35] (Trans/Appl Research) Diagnosis of diseases",null,null,null,null,null,null,null,"A28","Domestic fowl (Gallus gallus domesticus)",null,"[A28] Domestic fowl (Gallus gallus domesticus)",null,null,null,1,null,null," ",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PT27_1] Human Musculoskeletal Disorders",null,null,null,null,null,"[PR92] Reproductive toxicity"]
["[PT36]","[PT36] (Trans/Appl Research) Plant diseases",null,null,null,null,null,null,null,"A29_1","Quail (Coturnix coturnix)",null,"[A29_1] Quail (Coturnix coturnix)",null,null,null,1,1,null," ",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PT27_2] Human Dentistry",null,null,null,null,null,"[PR93] Developmental toxicity"]
["[PT37]","[PT37] (Trans/Appl Research) Non-regulatory toxicology and ecotoxicology",null,null,null,null,null,null,null,"A29_2","Other birds (other Aves)",null,"[A29_2] Other birds (other Aves)",1,null,null,1,null,null," ",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PT28] Human Immune Disorders",null,null,null,null,null,"[PR94] Neurotoxicity"]
["[PE40]","[PE40] Protection of the natural environment in the interests of the health or welfare of human beings or animals",null,null,null,null,null,null,null,"A30","Reptiles (Reptilia)",null,"[A30] Reptiles (Reptilia)",null,null,null,null,null,null," ",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PT29] Human Urogenital/Reproductive Disorders",null,null,null,null,null,"[PR95] Kinetics"]
["[PS41]","[PS41] Preservation of species",null,null,null,null,null,null,null,"A31","Rana (Rana temporaria and Rana pipiens)",null,"[A31] Rana (Rana temporaria and Rana pipiens)",null,null,null,null,1,null," ",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PT30] Human Sensory Organ Disorders (skin, eyes and ears)",null,null,null,null,null,"[PR96] Pharmaco-dynamics (incl safety pharmacology)"]
["[PE42]","[PE42] Higher education or training for the acquisition, maintenance or improvement of vocational skills",null,null,null,null,null,null,null,"A32","Xenopus (Xenopus laevis and Xenopus tropicalis)",null,"[A32] Xenopus (Xenopus laevis and Xenopus tropicalis)",null,null,null,null,1,null," ",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PT31] Human Endocrine/Metabolism Disorders",null,null,null,null,null,"[PR97] Phototoxicity"]
["[PF43]","[PF43] Forensic enquiries",null,null,null,null,null,null,null,"A33","Other Amphibians (other Amphibia)",null,"[A33] Other Amphibians (other Amphibia)",1,null,null,null,null,null," ",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PT32] Other Human Disorders",null,null,null,null,null,"Ecotoxicity",null,null,null,"[PR98] Acute toxicity"]
["[PG43]","[PG43] Maintenance of colonies of established genetically altered animals, not used in other procedures",null,null,null,null,null,null,null,"A34","Zebra fish (Danio rerio)",null,"[A34] Zebra fish (Danio rerio)",null,null,null,null,1,null," ",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PT33] Animal Diseases and Disorders",null,null,null,null,null,"[PR104] Safety testing in food and feed area",null,null,null,"[PR99] Chronic toxicity"]
["[PR51]","[PR51] (Regulatory use/ Routine production) Blood based products",1,null,null,null,null,null,null,"A35","Other Fish (other Pisces)",null,"[A35] Other Fish (other Pisces)",1,null,null,null,null,null," ",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PT34] Animal Welfare",null,null,null,null,null,"[PR105] Target animal safety",null,null,null,"[PR100] Reproductive toxicity"]
["[PR52]","[PR52] (Regulatory use/ Routine production) Monoclonal antibodies",1,null,null,null,null,null,null,"A36","Cephalopods (Cephalopoda)",null,"[A36] Cephalopods (Cephalopoda)",null,null,null,null,null,null," ",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PT35] Diagnosis of diseases",null,null,null,null,null,"[PR106] Other",null,null,null,"[PR101] Endocrine activity"]
["[PR53]","[PR53] (Regulatory use/ Routine production) Other",1,1,null,null,null,null,null," ",null,null,null,null,null,null,null,null,null," ",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PT36] Plant diseases",null,null,null,null,null,null,null,null,null,"[PR102] Bioaccumulation"]
["[PR61]","[PR61] (Regulatory use/ Quality control) Batch safety testing",1,null,null,null,null,null,null," ",null,null,null,null,null,null,null,null,null," ",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"[PT37] Non-regulatory toxicology and ecotoxicology",null,null,null,null,null,null,null,null,null,"[PR103] Other"]
["[PR62]","[PR62] (Regulatory use/ Quality control) Pyrogenicity testing",1,null,null,null,null,null,null," ",null,null,null,null,null,null,null,null,null," "]
["[PR63]","[PR63] (Regulatory use/ Quality control) Batch potency testing",1,null,null,null,null,null,null," ",null,null,null,null,null,null,null,null,null," "]
["[PR64]","[PR64] (Regulatory use/ Quality control) Other quality controls",1,1,null,null,null,null,null," ",null,null,null,null,null,null,null,null,null," "]
["[PR71]","[PR71] (Regulatory use) Other efficacy and tolerance testing",1,1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
["[PR81]","[PR81] (Regulatory use/Toxicity and../Acute and sub-acute) LD50, LC50",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
["[PR82]","[PR82] (Regulatory use/Toxicity and../Acute and sub-acute) Other lethal methods",1,1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
["[PR83]","[PR83] (Regulatory use/Toxicity and../Acute and sub-acute) Non lethal methods",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
["[PR84]","[PR84] (Regulatory use/Toxicity and..) Skin irritation/corrosion",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
["[PR85]","[PR85] (Regulatory use/Toxicity and..) Skin sensitisation",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
["[PR86]","[PR86] (Regulatory use/Toxicity and..) Eye irritation/corrosion",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
["[PR87]","[PR87] (Regulatory use/Toxicity and../Repeated dose toxicity) up to 28 days",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
["[PR88]","[PR88] (Regulatory use/Toxicity and../Repeated dose toxicity) 29 - 90 days",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
["[PR89]","[PR89] (Regulatory use/Toxicity and../Repeated dose toxicity) > 90 days",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
["[PR90]","[PR90] (Regulatory use/Toxicity and..) Carcinogenicity",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
["[PR91]","[PR91] (Regulatory use/Toxicity and..) Genotoxicity",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
["[PR92]","[PR92] (Regulatory use/Toxicity and..) Reproductive toxicity",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
["[PR93]","[PR93] (Regulatory use/Toxicity and..) Developmental toxicity",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
["[PR94]","[PR94] (Regulatory use/Toxicity and..) Neurotoxicity",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
["[PR95]","[PR95] (Regulatory use/Toxicity and..) Kinetics",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
["[PR96]","[PR96] (Regulatory use/Toxicity and..) Pharmaco-dynamics (incl safety pharmacology)",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
["[PR97]","[PR97] (Regulatory use/Toxicity and..) Phototoxicity",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
["[PR98]","[PR98] (Regulatory use/Toxicity and../Ecotoxicity) Acute toxicity",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
["[PR99]","[PR99] (Regulatory use/Toxicity and../Ecotoxicity) Chronic toxicity",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
[{"$f":"MID(B66,1,6)","v":"[PR100"},"[PR100] (Regulatory use/Toxicity and../Ecotoxicity) Reproductive toxicity",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
["[PR101","[PR101] (Regulatory use/Toxicity and../Ecotoxicity) Endocrine activity",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
[{"$f":"MID(B68,1,6)","v":"[PR102"},"[PR102] (Regulatory use/Toxicity and../Ecotoxicity) Bioaccumulation",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
[{"$f":"MID(B69,1,6)","v":"[PR103"},"[PR103] (Regulatory use/Toxicity and../Ecotoxicity) Other",1,1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
[{"$f":"MID(B70,1,6)","v":"[PR104"},"[PR104] (Regulatory use/Toxicity and..) Safety testing in food and feed area",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
[{"$f":"MID(B71,1,6)","v":"[PR105"},"[PR105] (Regulatory use/Toxicity and..) Target animal safety",1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
[{"$f":"MID(B72,1,6)","v":"[PR106"},"[PR106] (Regulatory use/Toxicity and..) Other",1,1,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
[null,"[PN107] Non-EU Purpose",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
[null,"[PB] Basic Research",1,"[PB1] Oncology",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
[null,"[PT] Translational/Applied Research",1,"[PB2] Cardiovascular Blood and Lymphatic System",null,null,null,null,null,null,null,null,null,null,null,null,null,null,null," "]
[null,"[PE] Protection of the natural environment in the interests of the health or welfare of human beings or animals",null,"[PB3] Nervous System"]
[null,"[PS] Preservation of species",null,"[PB4] Respiratory System"]
[null,"[PE] Higher education or training for the acquisition, maintenance or improvement of vocational skills",null,"[PB5] Gastrointestinal System including Liver"]
[null,"[PF] Forensic enquiries",null,"[PB6_1] Musculoskeletal System"]
[null,"[PG] Breeding/maintenance of colonies of established genetically altered animals, not used in other procedures",null,"[PB6_2] Dentistry"]
[null,"[PR] Regulatory use",1,"[PB7] Immune System",null,null,1]
[null,null,null,"[PB8] Urogenital/Reproductive System"]
[null,null,null,"[PB9] Sensory Organs (skin, eyes and ears)"]
[null,null,null,"[PB10] Endocrine System/Metabolism"]
[null,null,null,"[PB11] Multisystemic"]
[null,null,null,"[PB12] Ethology / Animal Behaviour /Animal Biology"]
[null,null,null,"[PB13] Other",null,1]
[null,null,null,"[PT21] Human Cancer"]
[null,null,null,"[PT22] Human Infectious Disorders"]
[null,null,null,"[PT23] Human Cardiovascular Disorders"]
[null,null,null,"[PT24] Human Nervous and Mental Disorders"]
[null,null,null,"[PT25] Human Respiratory Disorders"]
[null,null,null,"[PT26] Human Gastrointestinal Disorders including Liver"]
[null,null,null,"[PT27_1] Human Musculoskeletal Disorders"]
[null,null,null,"[PT27_2] Human Dentistry"]
[null,null,null,"[PT28] Human Immune Disorders"]
[null,null,null,"[PT29] Human Urogenital/Reproductive Disorders"]
[null,null,null,"[PT30] Human Sensory Organ Disorders (skin, eyes and ears)"]
[null,null,null,"[PT31] Human Endocrine/Metabolism Disorders"]
[null,null,null,"[PT32] Other Human Disorders",null,1]
[null,null,null,"[PT33] Animal Diseases and Disorders"]
[null,null,null,"[PT34] Animal Welfare"]
[null,null,null,"[PT35] Diagnosis of diseases"]
[null,null,null,"[PT36] Plant diseases"]
[null,null,null,"[PT37] Non-regulatory toxicology and ecotoxicology"]
[null,null,null,"[PE40] Protection of the natural environment in the interests of the health or welfare of human beings or animals"]
[null,null,null,"[PS41] Preservation of species"]
[null,null,null,"[PE42] Higher education or training for the acquisition, maintenance or improvement of vocational skills"]
[null,null,null,"[PF43] Forensic enquiries"]
[null,null,null,"[PG43] Maintenance of colonies of established genetically altered animals, not used in other procedures"]
[null,null,null,"[PR51]Routine production Blood based products",1]
[null,null,null,"[PR52]Routine production Monoclonal antibodies",1]
[null,null,null,"[PR53]Routine production Other",1,1]
[null,null,null,"[PR61]Quality control Batch safety testing",1]
[null,null,null,"[PR62]Quality control Pyrogenicity testing",1]
[null,null,null,"[PR63]Quality control Batch potency testing",1]
[null,null,null,"[PR64]Quality control Other quality controls",1,1]
[null,null,null,"[PR71] Other efficacy and tolerance testing",1,1]
[null,null,null,"[PR81]Toxicity and..Acute and sub-acute LD50, LC50",1]
[null,null,null,"[PR82]Toxicity and..Acute and sub-acute Other lethal methods",1,1]
[null,null,null,"[PR83]Toxicity and..Acute and sub-acute Non lethal methods",1]
[null,null,null,"[PR84]Toxicity and.. Skin irritation/corrosion",1]
[null,null,null,"[PR85]Toxicity and.. Skin sensitisation",1]
[null,null,null,"[PR86]Toxicity and.. Eye irritation/corrosion",1]
[null,null,null,"[PR87]Toxicity and..Repeated dose toxicity up to 28 days",1]
[null,null,null,"[PR88]Toxicity and..Repeated dose toxicity 29 - 90 days",1]
[null,null,null,"[PR89]Toxicity and..Repeated dose toxicity > 90 days",1]
[null,null,null,"[PR90]Toxicity and.. Carcinogenicity",1]
[null,null,null,"[PR91]Toxicity and.. Genotoxicity",1]
[null,null,null,"[PR92]Toxicity and.. Reproductive toxicity",1]
[null,null,null,"[PR93]Toxicity and.. Developmental toxicity",1]
[null,null,null,"[PR94]Toxicity and.. Neurotoxicity",1]
[null,null,null,"[PR95]Toxicity and.. Kinetics",1]
[null,null,null,"[PR96]Toxicity and.. Pharmaco-dynamics (incl safety pharmacology)",1]
[null,null,null,"[PR97]Toxicity and.. Phototoxicity",1]
[null,null,null,"[PR98]Toxicity and..Ecotoxicity Acute toxicity",1]
[null,null,null,"[PR99]Toxicity and..Ecotoxicity Chronic toxicity",1]
[null,null,null,"[PR100]Toxicity and..Ecotoxicity Reproductive toxicity",1]
[null,null,null,"[PR101]Toxicity and..Ecotoxicity Endocrine activity",1]
[null,null,null,"[PR102]Toxicity and..Ecotoxicity Bioaccumulation",1]
[null,null,null,"[PR103]Toxicity and..Ecotoxicity Other",1,1]
[null,null,null,"[PR104]Toxicity and.. Safety testing in food and feed area",1]
[null,null,null,"[PR105]Toxicity and.. Target animal safety",1]
[null,null,null,"[PR106]Toxicity and.. Other",1,1]
[null,null,null,"[PN107] Non-EU Purpose"]