SGLT2 inhibitors: updated advice on increased risk of lower-limb amputation (mainly toes)

2017-03-22T15:25:06+00:00

Canagliflozin may increase the risk of lower-limb amputation (mainly toes) in patients with type 2 diabetes. Evidence does not show an increased risk for dapagliflozin and empagliflozin, but the risk may be a class effect. P…