The SARS outbreak of 2002–2003 presented clinicians with a new, life-threatening disease for which they had no experience in treating and no research on the effectiveness of treatment options. The World Health Organization (WHO) expert panel on SARS treatment requested a systematic review and comprehensive summary of treatments used for SARS-infected patients in order to guide future treatment and identify priorities for research.
Stockman, L.; Bellamy, R.; Garner, P. SARS: A Systematic Review of Treatment Effects. PLoS Medicine (2006) 3 (9) 1525-1531. [DOI: 10.1371/journal.pmed.0030343]